James Binley, Ph.D. and colleagues identify a lineage of HIV-1- neutralizing antibodies that target the envelope trimer apex

To date, long recognition loops have been a hallmark of apex-targeting antibodies. The authors identify a lineage of HIV-1-neutralizing antibodies that target the envelope trimer apex. The N90-VRC38 lineage uses a loop of average length—a feature that may make it a useful prototype for vaccine design. See link below for full-text article.